Fibrin Sealant
Fibrin Glue · Tisseel · Evicel · Fibrin Glue Applicator
A two-part biologic glue: human fibrinogen levelfy-BRIN-uh-jen LEV-ulA blood test that measures fibrinogen, a protein made by the liver that the body turns into fibrin to form clots.Full entry in one syringe and human thrombinTHROM-binAn enzyme in the blood that turns fibrinogen into fibrin, the threads that hold a blood clot together.thromb/o clot-in substanceFull entry in the other. The two meet at the tip of a dual-syringe applicator (or spray tip) and set into a fibrin clot. Comes as a freeze-dried kit to reconstitute or as a frozen prefilled syringe to thaw.
On the table
What it does, the lengths it comes in and what experienced techs know about it.
What it’s for
Applied to tissue surfaces to stop oozing, bind tissues together, or seal air and blood leaks. Uses include lung air leaks, liver and spleenspleenAn organ in the upper left abdomen that filters the blood and helps fight infection.splen/o spleenFull entry surfaces that are hard to sutureSOO-cherA stitch, or the thread used to stitch, that holds the edges of a wound or incision together.Full entry , and vascular anastomosisuh-nas-tuh-MOH-sisA connection between two tube-shaped structures, such as two ends of bowel or two blood vessels, made by surgery or found naturally.Full entry (with sutures). Opened when the surgeon requests it.
Lengths and variants
Tisseel: freeze-dried kit or frozen prefilled syringe, in 2, 4 and 10 mL sizes. Evicel: kit of two frozen syringes (fibrinogen levelfy-BRIN-uh-jen LEV-ulA blood test that measures fibrinogen, a protein made by the liver that the body turns into fibrin to form clots.Full entry and thrombinTHROM-binAn enzyme in the blood that turns fibrinogen into fibrin, the threads that hold a blood clot together.thromb/o clot-in substanceFull entry ) with a spray applicator, 2, 4 and 10 mL total volumes.
What experienced techs know
What techs who reach for it every day know about it.Pro
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2 sources
- Howe. Pharmacology for the Surgical Technologist. 5th ed. Chapter 9 (Medications That Affect Coagulation), p. 121
- Fuller. Surgical Technology: Principles and Practice. 8th ed. Chapter 12 (Perioperative Pharmacology), p. 236 and 238
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