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acetylcholine

A chemical messenger that nerves release to signal muscles, glands and other nerves.

uh-see-tul-KOH-leen noun

What it means

A neurotransmitterNOOR-oh-trans-mit-erA chemical that a nerve cell releases to pass a signal to another nerve, muscle or gland cell.neur/o nervetrans- acrossmitt send-er one that doesFull entry used where nerves meet skeletal muscle (telling muscles to contract), throughout the parasympathetic nervous system ("rest and digest": slower heart rate, more saliva, gut movement, bladder emptying) and in the brain, where it helps memory. Drugs that block it are anticholinergican-tee-koh-lin-ER-jikA drug or effect that blocks acetylcholine, a nerve messenger, in parts of the nervous system.anti- againstcholinergic acting like acetylcholineFull entry ; drugs that boost it include those used in myasthenia gravismy-us-THEE-nee-uh GRAV-isA long-term autoimmune disease in which antibodies block the signals passing from nerves to muscles.my/o muscle-asthenia weaknessgravis seriousFull entry and Alzheimer disease.

At a glance

AbbreviationsACh
Spanishacetilcolina
Also writtenACh

Related terms

autonomic nervous system

The part of the nervous system that controls body functions without conscious thought, such as heart rate, breathing and digestion.

neurotransmitter

A chemical that a nerve cell releases to pass a signal to another nerve, muscle or gland cell.

myasthenia gravis

A long-term autoimmune disease in which antibodies block the signals passing from nerves to muscles.

anticholinergic

A drug or effect that blocks acetylcholine, a nerve messenger, in parts of the nervous system.

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