What it means
A bisphosphonatebis-FOS-fuh-naytA drug that slows the breakdown of bone.Full entry that slows the cells that break down bone, so bones stay denser and break less often. It is used for osteoporosisos-tee-oh-puh-ROH-sisA condition in which bones lose density and become thin, weak and easy to break.oste/o bonepor/o pore, small opening-osis abnormal conditionFull entry and Paget disease of bone, often as one tablet a week. It can irritate and ulcerate the esophagus if not taken correctly. Rare problems with long use include jawbone damage (osteonecrosis of the jaw) and unusual thigh-bone fractures.
For the nurse
Teach the client to take it first thing in the morning with a full glass of plain water, on an empty stomach, and to stay sitting or standing and not eat, drink or take other medicines for at least 30 minutes. They should get enough calcium and vitamin D, taken at another time of day, have regular dental care, and report heartburn, pain on swallowing, or new thigh or groin pain.
At a glance
| Drug class | bisphosphonate |
|---|---|
| Brand names | Fosamax, Binosto |
| Spanish | alendronato |
| Also written | Fosamax, Binosto |
Related terms
calcium
A mineral that builds bones and teeth and that nerves, muscles, the heart and blood clotting need to work.
osteoporosis
A condition in which bones lose density and become thin, weak and easy to break.
vitamin D
A fat-soluble vitamin that the skin makes in sunlight and that helps the body absorb calcium for strong bones.
bisphosphonate
A drug that slows the breakdown of bone.