What it means
A xanthine oxidase inhibitor: it blocks an enzyme the body needs to make uric acid. It is taken long term to prevent gout flares and uric acid kidney stones, and to protect the kidneys when cancer treatment breaks down many cells at once. It does not treat a gout attack that has already started. A rare but serious reaction is a severe skin rash.
For the nurse
Teach the client to drink plenty of fluids (often 2 to 3 liters a day unless restricted) and to take it after meals to limit stomach upset. Tell them to stop it and call the provider for any rash. Gout attacks may happen more often in the first months, so other drugs may be given with it.
At a glance
| Drug class | antigout agent (xanthine oxidase inhibitor) |
|---|---|
| Brand names | Zyloprim, Aloprim (IV) |
| Spanish | alopurinol |
| Also written | Zyloprim, Aloprim |
Related terms
-lith
A word ending that means stone or a hard mass.