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Dictionary · Drug

amiodarone

A drug used to treat and prevent serious abnormal heart rhythms.

am-ee-OH-duh-rone nounHigh-alert drugBoxed warningBeers Criteria

What it means

A class III antiarrhythmic that slows the heart's electrical recovery between beats. It is used for ventricular tachycardia and ventricular fibrillation (including during cardiac arrest) and to control atrial fibrillationAY-tree-ul fib-rih-LAY-shunAn irregular heart rhythm in which the upper chambers of the heart quiver instead of beating in an organized way.atri/o atrium (upper heart chamber)fibrill/o small fibers, quivering-ation processFull entry . It stays in the body for weeks to months. Long-term use can harm the lungs, liver, thyroid and eyes and cause sun sensitivity and a blue-gray skin color, and the oral form has a boxed warning. IV amiodarone is on ISMP's high-alert list (IV antiarrhythmics); the tablets are not. It raises the levels of warfarin and digoxin. Its name can be confused with amantadineuh-MAN-tuh-deenA drug used for Parkinson disease and its movement side effects, first made as an antiviral for influenza.Full entry .

For the nurse

During IV use, keep the client on a cardiac monitor and check blood pressure and heart rate often; low blood pressure and slow heart rate are common. For long-term use, expect baseline and follow-up lung, liver and thyroid tests and eye exams. Teach the client to report a new cough or shortness of breath, and to use sun protection.

At a glance

Drug classantiarrhythmic (class III)
Brand namesPacerone, Nexterone
Spanishamiodarona
Also writtenPacerone, Nexterone

Easy to confuse with

amantadine

A drug used for Parkinson disease and its movement side effects, first made as an antiviral for influenza.

Related terms

digoxin

A drug that makes the heart beat more strongly and more slowly.

arrhythmia

A heart rhythm that is not normal: too fast, too slow or irregular.

atrial fibrillation

An irregular heart rhythm in which the upper chambers of the heart quiver instead of beating in an organized way.

ventricular tachycardia

A fast heart rhythm that starts in the lower chambers of the heart (the ventricles), usually over 100 beats per minute.

ventricular fibrillation

A heart rhythm in which the lower chambers quiver in a fast, chaotic way instead of pumping.

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