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Dictionary · Drug

angiotensin II receptor blocker

A drug that blocks the hormone angiotensin II so blood vessels relax and blood pressure falls.

an-jee-oh-TEN-sin too ree-SEP-ter BLOK-er nounBoxed warning

What it means

ARBs treat high blood pressure and heart failure and help protect the kidneys in diabetes. Their generic names end in -sartan: losartan, valsartan, irbesartan, olmesartan, candesartan. They work much like ACE inhibitors but rarely cause the dry cough those drugs can cause. They can raise the potassiumpuh-TAS-ee-umA mineral in the blood that nerves and muscles, including the heart, need in order to work.Full entry level and, rarely, cause swelling of the face and throat (angioedemaan-jee-oh-eh-DEE-muhSwelling in the deeper layers of the skin and the lining of the mouth, throat or gut.angi/o vesseledema swellingFull entry ).

For the nurse

Check the blood pressure before each dose and teach the client to stand up slowly. Watch the potassium level and kidney function, and tell the client not to use potassium supplements or salt substitutes unless prescribed. The boxed warning is for harm to an unborn baby: these drugs are stopped as soon as pregnancy is known.

Remember it

"-sartan" means ARB.

At a glance

Spanishantagonista del receptor de angiotensina II
Also writtenARB, ARBs, angiotensin receptor blocker, angiotensin receptor blockers

Related terms

hyperkalemia

A blood potassium level above normal, over 5.0 mEq/L.

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

heart failure

A long-term condition in which the heart cannot pump enough blood to meet the body's needs.

angioedema

Swelling in the deeper layers of the skin and the lining of the mouth, throat or gut.

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