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anti-factor Xa level

A blood test that measures how strongly heparin or a similar drug is blocking clotting factor Xa.

AN-tee FAK-ter TEN-AY LEV-ul noun

What it means

Heparin and low molecular weight heparins (such as enoxaparin) work largely by blocking factor Xa, a key step in clotting. This test measures that effect directly. It guides unfractionated heparin infusions in many hospitals, and it checks enoxaparin dosing in clients with kidney disease, very high or low body weight, or pregnancy.

For the nurse

Time the draw exactly as ordered and record when the last dose was given; for a heparin infusion, draw from the arm without the infusion.

At a glance

Normal rangeNo anticoagulant: none detected. Usual targets: heparin infusion 0.3–0.7 units/mL; twice-daily enoxaparin about 0.5–1.0 units/mL, drawn about 4 hours after a dose. Targets vary by protocol.
Also writtenanti-Xa, anti-Xa level, heparin anti-Xa

Related terms

anticoagulant

A drug that slows the blood's ability to form clots.

heparin

An anticoagulant drug, given by injection or IV, that keeps blood clots from forming or growing.

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