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Dictionary · Drug

captopril

An ACE inhibitor taken by mouth to lower blood pressure and to treat heart failure.

KAP-toh-pril nounBoxed warning

What it means

An angiotensin-converting enzyme (ACE) inhibitor, the first in its class. It relaxes blood vessels and lowers the body's salt and water retention. It acts faster and for a shorter time than most ACE inhibitors, so it is taken two or three times a day. Side effects include a dry cough, high potassium, low blood pressure with the first dose and, rarely, swelling of the face, lips and throat (angioedema).

For the nurse

Give it 1 hour before meals. Check blood pressure, potassium and kidney tests. Teach the client to rise slowly, to avoid salt substitutes that contain potassium, and to seek emergency help for any swelling of the face, tongue or throat. It must not be taken in pregnancy.

At a glance

Drug classangiotensin-converting enzyme (ACE) inhibitor
Brand namesCapoten (older brand)
Spanishcaptopril

Related terms

hyperkalemia

A blood potassium level above normal, over 5.0 mEq/L.

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

heart failure

A long-term condition in which the heart cannot pump enough blood to meet the body's needs.

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