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Dictionary · Drug

cephalexin

A first-generation cephalosporin antibiotic taken by mouth for skin, urinary, ear and other bacterial infections.

sef-uh-LEK-sin noun

What it means

A beta-lactam antibiotic that works mostly against gram-positive bacteria such as staphylococci and streptococci. It is used for cellulitissel-yoo-LY-tisA bacterial infection of the deeper layers of the skin and the tissue just under it.cellul small cell-itis inflammationFull entry , other skin infections, some urinary tract infectionYUR-ih-nair-ee TRAKT in-FEK-shunAn infection anywhere in the urinary tract: the kidneys, ureters, bladder or urethra.Full entry , strep throat and ear infections. Side effects include diarrhea, nausea and rash.

For the nurse

Ask about allergies before giving: a small number of people with a penicillin allergy also react to cephalosporins, and those with a severe penicillin reaction need the provider's review. Teach the client to finish the course and report watery diarrhea, which can mean C. difficile.

At a glance

Drug classantibiotic (cephalosporin, first generation)
Brand namesKeflex
Spanishcefalexina
Also writtenKeflex

Easy to confuse with

levetiracetam

An anticonvulsant drug, given by mouth or IV, used to prevent and treat seizures.

Related terms

C. difficile

Clostridioides difficile, a spore-forming bacterium that can infect the colon (the large intestine).

antibiotic

A drug that kills bacteria or stops them from growing.

Staphylococcus

A group of round bacteria that grow in grape-like clusters and often live on the skin and in the nose.

cellulitis

A bacterial infection of the deeper layers of the skin and the tissue just under it.

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