Skip to main content
CSTSetup
Dictionary · Drug

chlorpromazine

An older antipsychotic drug, also used for severe nausea and vomiting and for hiccups that will not stop.

klor-PROH-muh-zeen nounBoxed warningBeers Criteria

What it means

A first-generation (typical) antipsychotic of the phenothiazine group, used for schizophrenia and other psychoses. Side effects include sleepiness, dizziness on standing (orthostatic hypotension), dry mouth and constipation, sun sensitivity, and movement problems: extrapyramidal symptoms and, after long use, tardive dyskinesia. A rare, dangerous reaction is neuroleptic malignant syndrome. Like all antipsychotics, it has a boxed warning for a higher death rate in older adults with dementia-related psychosis. Its name looks like chlordiazepoxideklor-dy-az-uh-POK-sideA long-acting benzodiazepine used for anxiety and for alcohol withdrawal.Full entry .

For the nurse

Check blood pressure lying and standing and help the client get up slowly. Watch for stiffness, restlessness, tremor or odd movements of the face and tongue, and report a high fever with muscle rigidity at once. Teach sun protection. Avoid getting the liquid on your skin, because it can cause a rash.

At a glance

Drug classfirst-generation antipsychotic (phenothiazine)
Brand namesThorazine (former US brand)
Spanishclorpromazina
Also writtenThorazine

Easy to confuse with

chlordiazepoxide

A long-acting benzodiazepine used for anxiety and for alcohol withdrawal.

Related terms

hallucination

Hearing, seeing, feeling, smelling or tasting something that is not really there.

Filed under

Look up another word