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Dictionary · Drug

clonidine

A drug that acts in the brain to lower nerve signals that tighten blood vessels, used for high blood pressure and other conditions.

KLON-ih-deen nounBeers Criteria

What it means

A centrally acting alpha-2 agonist. By calming the sympathetic nervous system, it lowers blood pressure and heart rate. It is used for high blood pressure, ADHD (extended-release form), and sometimes to ease withdrawal symptoms; an epidural form is used for severe cancer pain. It comes as tablets, a weekly skin patch and an injection. Dry mouth, drowsiness, dizziness and constipation are common.

For the nurse

Check blood pressure and pulse before giving. Teach the client never to stop it suddenly, because blood pressure can rebound to dangerous levels, and to rise slowly. Rotate patch sites and remove the old patch. Do not confuse it with clonazepam or clozapine.

At a glance

Drug classcentrally acting alpha-2 adrenergic agonist (antihypertensive)
Brand namesCatapres, Catapres-TTS, Duraclon
Spanishclonidina
Also writtenCatapres, Catapres-TTS, Duraclon

Easy to confuse with

clonazepam

A long-acting benzodiazepine drug used for seizure disorders and panic disorder.

clozapine

An atypical antipsychotic drug used for schizophrenia when other antipsychotics have not worked.

Related terms

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

autonomic nervous system

The part of the nervous system that controls body functions without conscious thought, such as heart rate, breathing and digestion.

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