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creatinine

A waste product of muscle that the kidneys remove from the blood; its blood level is used to measure how well the kidneys work.

kree-AT-uh-neen noun

What it means

Muscles make creatinine at a steady rate, and healthy kidneys filter it out into the urine. When the kidneys are not working well, creatinine builds up in the blood, so the serum creatinine is the main lab test of kidney function, often read together with blood urea nitrogenblud yoo-REE-uh NY-truh-jenA blood test that measures urea nitrogen, a waste product made when the body breaks down protein.Full entry (BUN). It is also used to work out the estimated glomerular filtration rate (eGFR).

For the nurse

Check the creatinine before giving drugs that the kidneys clear or that can harm them, and before tests with IV contrast dye. Report a rising value, along with falling urine output.

At a glance

Normal rangeAdult male 0.6–1.2 mg/dL [53–106 µmol/L]; adult female 0.5–1.1 mg/dL [44–97 µmol/L]. Each lab sets its own reference range.
AbbreviationsCr; SCr (serum creatinine)
Spanishcreatinina
Also writtenCr, creatinine level, serum creatinine, creatinine levels

Related terms

chronic kidney disease

Kidney damage or reduced kidney function that lasts longer than three months.

renal

Relating to the kidneys.

blood urea nitrogen

A blood test that measures urea nitrogen, a waste product made when the body breaks down protein.

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