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D-dimer

A blood test that measures a protein fragment released when a blood clot breaks down.

DEE-DY-mer noun

What it means

When the body breaks down a clot (fibrinolysisfy-brin-OL-ih-sisThe body's process of breaking down a blood clot once it is no longer needed.fibrin/o fibrin, the protein threads of a clot-lysis breaking downFull entry ), fragments called D-dimers appear in the blood. A normal result makes a significant clot, such as a deep vein thrombosisDEEP VAYN throm-BOH-sisA blood clot in a deep vein, most often in the leg or pelvis.thromb/o clot-osis conditionFull entry or pulmonary embolismPUL-muh-nair-ee EM-buh-liz-umA blockage of an artery in the lungs, usually by a blood clot that has traveled there from elsewhere in the body.pulmon/o lung-ary relating toembol/o plug-ism conditionFull entry , unlikely. A high result is not specific: it can come from clots but also from recent surgery, pregnancy, infection, cancer, older age or disseminated intravascular coagulationdih-SEM-ih-nay-tid in-truh-VAS-kyuh-ler koh-ag-yuh-LAY-shunA disorder in which clotting is switched on throughout the blood vessels until the clotting factors are used up.intra- withinvascul/o vesselcoagul/o clottingFull entry , so more tests are usually needed.

For the nurse

Know the reason for the test and look for signs of a clot: one-sided leg swelling and pain, or sudden shortness of breath and chest pain.

At a glance

Normal rangeBelow 500 ng/mL FEU [below 0.5 mg/L FEU]; labs and units vary.
Also writtenD dimer, d-dimer

Related terms

deep vein thrombosis

A blood clot in a deep vein, most often in the leg or pelvis.

pulmonary embolism

A blockage of an artery in the lungs, usually by a blood clot that has traveled there from elsewhere in the body.

disseminated intravascular coagulation

A disorder in which clotting is switched on throughout the blood vessels until the clotting factors are used up.

fibrinolysis

The body's process of breaking down a blood clot once it is no longer needed.

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