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Dictionary · Drug

ergotamine

An ergot drug that narrows blood vessels, taken at the start of a migraine or cluster headache to stop it.

er-GOT-uh-meen nounBoxed warning

What it means

An ergot alkaloid used under the tongue, or with caffeine (Cafergot), to abort a headache. It narrows blood vessels throughout the body, so too much can cut off blood flow to the hands, feet and other organs (ergotism). Taking it with strong CYP3A4 inhibitors, such as some antibiotics and HIV drugs, can cause dangerous loss of blood flow.

For the nurse

Teach the client to take it at the first sign of the headache, not to exceed the weekly limit, and to report cold, numb or painful fingers or toes and chest pain. It is not used in pregnancy, coronary artery disease or uncontrolled high blood pressure.

At a glance

Drug classergot alkaloid (antimigraine)
Brand namesErgomar; with caffeine: Cafergot
Also writtenErgomar

Related terms

coronary artery disease

Narrowing of the arteries that supply blood to the heart muscle, most often from fatty plaque buildup.

methylergonovine

An ergot drug that makes the uterus contract firmly, given after birth.

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