What it means
A histamine-2 receptor antagonist: it blocks histamine's signal to the acid-making cells of the stomach. It is used for heartburn, gastroesophageal reflux diseasegas-troh-ih-sof-uh-JEE-ul REE-fluks dih-ZEEZA long-term condition in which stomach contents, including acid, flow back up into the esophagus.gastr/o stomachesophag/o esophagus-al relating toFull entry , stomach and duodenal ulcers, and to prevent stress ulcers in very ill clients. It is usually well tolerated; headache, dizziness and constipation or diarrhea can occur.
For the nurse
The dose is lowered when kidney function is poor. Watch older adults for confusion, and report new confusion; H2 blockers are among drugs the Beers Criteria advise avoiding in people with delirium. Teach the client to avoid smoking and foods that bring on symptoms.
At a glance
| Drug class | histamine-2 (H2) receptor antagonist |
|---|---|
| Brand names | Pepcid, Pepcid AC |
| Spanish | famotidina |
| Also written | Pepcid, Pepcid AC |
Related terms
gastroesophageal reflux disease
A long-term condition in which stomach contents, including acid, flow back up into the esophagus.
sucralfate
A drug taken by mouth that forms a protective coating over ulcers in the stomach and duodenum.
cimetidine
An H2 blocker taken by mouth that lowers the amount of acid the stomach makes.
pantoprazole
A proton pump inhibitor, taken by mouth or IV, that strongly lowers the amount of acid the stomach makes.