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Dictionary · Drug

flucytosine

An oral antifungal drug used with other antifungals to treat serious yeast and fungal infections.

floo-SY-toe-seen nounBoxed warning

What it means

An antifungal capsule that stops fungal cells from making the material they need to grow. It is almost never used alone, because fungi quickly become resistant to it; it is given with amphotericin B for serious infections such as cryptococcal meningitis and some Candida infections. The kidneys clear it, so kidney problems raise the blood level.

For the nurse

Watch blood counts, kidney function and liver tests: it can suppress the bone marrow and is used with great care when the kidneys are weak. Report sore throat, fever, unusual bruising or bleeding. Nausea is common; taking the capsules a few at a time over 15 minutes can help.

At a glance

Drug classantifungal (pyrimidine analog)
Brand namesAncobon
Spanishflucitosina

Related terms

antibiotic

A drug that kills bacteria or stops them from growing.

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