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Dictionary · Drug

glycopyrrolate

An anticholinergic drug that dries up saliva and airway secretions and keeps the heart rate from falling too low.

gly-koh-PEER-oh-late noun

What it means

A drug that blocks acetylcholine at muscarinic receptors but does not easily enter the brain. In surgery it is given IV to reduce secretions and, with neostigminenee-oh-STIG-meenA drug that blocks the enzyme that breaks down acetylcholine, so nerve signals to muscles get stronger.Full entry , to prevent a slow heart rate when muscle relaxants are reversed. It is also used for chronic drooling, for noisy secretions near the end of life, for peptic ulcers, and inhaled for COPD.

For the nurse

Watch for dry mouth, urinary retention, constipation, blurred vision and a fast heart rate. Teach the client to avoid overheating, since it reduces sweating.

At a glance

Drug classanticholinergic (antimuscarinic)
Brand namesRobinul, Cuvposa (oral solution), Glycate
Also writtenRobinul, Cuvposa

Related terms

bradycardia

A heart rate slower than normal; in an adult, fewer than 60 beats per minute.

secretion

A substance a gland or cell makes and releases, such as mucus, saliva, sweat or a hormone.

neostigmine

A drug that blocks the enzyme that breaks down acetylcholine, so nerve signals to muscles get stronger.

death rattle

A noisy, gurgling or rattling sound with breathing in the last hours or days of life.

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