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hepatitis B surface antigen

A blood test for a protein from the outer coat of the hepatitis B virus.

hep-uh-TY-tis bee SUR-fis AN-tih-jen noun

What it means

The surface antigen appears in the blood when a person is infected with hepatitis B virus. A positive test means current infection, either new (acute) or long-term (chronic, when it stays positive for more than 6 months), and that the person can pass the virus on through blood and body fluids. It is read with other hepatitis B tests; the antibody to the surface antigen (anti-HBs) shows immunity from vaccination or past infection.

For the nurse

It is a routine prenatal test. A newborn whose birthing parent is positive receives hepatitis B vaccine and hepatitis B immune globulin (HBIG) within 12 hours of birth.

At a glance

Normal rangeNegative
Also writtenHBsAg

Related terms

vaccine

A product that trains the immune system to protect the body against a specific disease.

hepatitis B

A liver infection caused by the hepatitis B virus.

lamivudine

An oral antiviral drug used with other drugs to treat HIV, and alone to treat chronic hepatitis B.

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