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Dictionary · Eponym

Huntington disease

An inherited brain disease in which certain nerve cells slowly break down over many years.

HUN-ting-tun dih-ZEEZ noun

What it means

A genetic disease passed down in an autosomal dominant way: a child of an affected parent has a 50% chance of inheriting it. Symptoms usually start between ages 30 and 50 and slowly worsen: jerky, dance-like movements called chorea, problems with thinking and memory, and mood and behavior changes such as depression and irritability. There is no cure; medicines ease the movements and mood symptoms. It is named after George Huntington, the American physician who described it in 1872.

For the nurse

Plan for safety (falls, choking, weight loss from constant movement and swallowing problems), screen for depression and suicide risk, and support the family, who may want genetic counseling.

At a glance

Also writtenHuntington's disease, Huntington’s disease, Huntington chorea, Huntington's chorea

Related terms

dysphagia

Difficulty swallowing.

dementia

A long-term, usually worsening decline in memory and thinking that is serious enough to affect daily life.

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