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Dictionary · Drug

hydralazine

A vasodilator that lowers blood pressure by relaxing the walls of the arteries.

hy-DRAL-uh-zeen noun

What it means

A direct-acting vasodilatorvay-zoh-DY-lay-terA drug that widens blood vessels by relaxing the muscle in their walls.vas/o vesseldilat to widen-or one that doesFull entry given by mouth, IV or IM. It is used for high blood pressure, for severe high blood pressure in pregnancy (as in preeclampsiapree-ih-KLAMP-see-uhA disorder of pregnancy, starting after 20 weeks, that affects the blood vessels and organs such as the kidneys, liver and brain.pre- beforeeclampsia Full entry ), and with isosorbide dinitrate for heart failure. As the blood pressure drops, the heart may speed up (reflex tachycardia); headache, flushing and fluid retention are also common. Long-term high doses can cause a lupus-like reaction. Its name looks like hydrochlorothiazidehy-droh-klor-oh-THY-uh-zideA thiazide diuretic that lowers blood pressure and reduces swelling by helping the kidneys remove salt and water.Full entry , hydromorphonehy-droh-MOR-foneA strong opioid pain medicine, given by mouth, by injection or into a vein.Full entry and hydroxyzinehy-DROK-sih-zeenA sedating antihistamine used for anxiety, itching and nausea, and to calm clients before or after surgery.Full entry .

For the nurse

After an IV dose, check blood pressure and heart rate often, as the facility's protocol directs, and in pregnancy watch the fetal heart rate. Teach the client to rise slowly and to report joint pain, fever or a rash.

At a glance

Drug classvasodilator (antihypertensive)
Brand namesApresoline (former US brand)
Spanishhidralazina
Also writtenApresoline

Easy to confuse with

hydromorphone

A strong opioid pain medicine, given by mouth, by injection or into a vein.

hydrochlorothiazide

A thiazide diuretic that lowers blood pressure and reduces swelling by helping the kidneys remove salt and water.

hydroxyzine

A sedating antihistamine used for anxiety, itching and nausea, and to calm clients before or after surgery.

Related terms

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

heart failure

A long-term condition in which the heart cannot pump enough blood to meet the body's needs.

preeclampsia

A disorder of pregnancy, starting after 20 weeks, that affects the blood vessels and organs such as the kidneys, liver and brain.

vasodilator

A drug that widens blood vessels by relaxing the muscle in their walls.

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