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Dictionary · Drug

hydrocortisone

A corticosteroid drug that is the same as the body's own cortisol, given by mouth, IV, on the skin or rectally.

hy-droh-KOR-tih-sone noun

What it means

A drug form of cortisolKOR-tih-solA steroid hormone made by the adrenal glands that helps control blood sugar, blood pressure, stress and inflammation.Full entry . By mouth and IV it replaces cortisol in adrenal insufficiency (Addison diseaseAD-ih-sun dih-ZEEZA condition in which the adrenal glands do not make enough cortisol and often not enough aldosterone.Full entry ) and is given by IV in adrenal crisis and some severe illnesses. Unlike most steroid drugs, it also helps the body hold sodium (a mineralocorticoidmin-er-uh-loh-KOR-tih-koydA steroid hormone, or a drug that acts like one, that makes the kidneys keep sodium and water and remove potassium.mineral saltscortic/o cortex-oid likeFull entry effect). Creams treat itchy, inflamed skin, and rectal forms treat hemorrhoids and colitis. Its IV brand Solu-Cortef looks like Solu-Medrol, a brand of methylprednisolonemeth-il-pred-NIS-oh-loneA corticosteroid drug given by mouth, IV or injection to reduce inflammation and calm the immune system.Full entry .

For the nurse

Clients on long-term replacement must not stop it suddenly and may need extra doses during illness or surgery; teach them to wear medical ID. Do not abbreviate the name: ISMP lists "HCT" as error-prone. Check the label carefully against methylprednisolone.

At a glance

Drug classcorticosteroid (glucocorticoid and mineralocorticoid)
Brand namesSolu-Cortef, Cortef, Anusol-HC
Spanishhidrocortisona
Also writtenSolu-Cortef, Cortef

Easy to confuse with

methylprednisolone

A corticosteroid drug given by mouth, IV or injection to reduce inflammation and calm the immune system.

Related terms

corticosteroid

A drug that acts like the hormones of the adrenal glands, used mainly to calm inflammation and the immune system.

cortisol

A steroid hormone made by the adrenal glands that helps control blood sugar, blood pressure, stress and inflammation.

Addison disease

A condition in which the adrenal glands do not make enough cortisol and often not enough aldosterone.

HCT (hydrocortisone)

HCT written for the drug hydrocortisone: an abbreviation ISMP lists as error-prone. It is not the lab value Hct (hematocrit).

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