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hypertrophy

An increase in the size of an organ or tissue because its cells grow larger.

hy-PER-truh-fee noun

Word parts

What it means

Tissue grows bigger when its cells enlarge, usually because they are working harder. Skeletal muscles hypertrophy with exercise. The heart's left ventricle thickens (left ventricular hypertrophy) after years of high blood pressure, which can make it stiff. It differs from hyperplasia, where the number of cells increases, as in benign prostatic hyperplasiabee-NINE proh-STAT-ik hy-per-PLAY-zhuhA prostate gland that has grown larger than normal, from growth that is not cancer.hyper- more than normalplas growth or formation-ia conditionFull entry .

At a glance

AbbreviationsLVH (left ventricular hypertrophy)
Spanishhipertrofia
Also writtenhypertrophic, hypertrophied

Easy to confuse with

atrophy

The wasting away or shrinking of a body part, such as a muscle or organ.

Related terms

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

hyper-

A word beginning that means above, over or more than normal.

atrophy

The wasting away or shrinking of a body part, such as a muscle or organ.

cardiomyopathy

A disease of the heart muscle itself that makes it harder for the heart to pump blood.

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