What it means
IgE antibodies attach to mast cells and basophils. When a person who is sensitized meets the allergen again, the allergen binds to this IgE and the cells release histamine and other chemicals, causing hives, sneezing, wheezing or, at worst, anaphylaxisan-uh-fuh-LAK-sisA sudden, severe allergic reaction that affects the whole body.ana- away, against-phylaxis protectionFull entry . Blood tests can measure total IgE or IgE to specific allergens.
At a glance
| Also written | immunoglobulin E |
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Related terms
allergy
A reaction of the immune system to a substance that is harmless to most people.
anaphylaxis
A sudden, severe allergic reaction that affects the whole body.
immune system
The body's defense system of cells, tissues and organs that fights germs and other foreign substances.
hypersensitivity
An overreaction of the immune system to a substance that is usually harmless.