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Dictionary · Drug

inotropic

Changing the force with which the heart muscle contracts; an inotropic drug is one that does this.

in-oh-TROH-pik adjective

Word parts

ino fiber, muscle-tropic acting on, turning

What it means

A positive inotropic drug makes the heart pump more strongly; examples are digoxindih-JOK-sinA drug that makes the heart beat more strongly and more slowly.Full entry , dobutaminedoh-BYOO-tuh-meenAn IV drug that makes the heart muscle squeeze harder, used for short-term support of a weak heart.Full entry and milrinone, used in heart failure and some kinds of shock. A negative inotropic drug weakens the squeeze, as beta blockers and some calcium channel blockers do. The noun form is inotrope.

For the nurse

IV inotropic drugs are on the ISMP list of high-alert medications. Run them on a pump, keep the client on a cardiac monitor and check blood pressure, heart rate and urine output closely.

At a glance

Drug classinotrope (positive or negative)
Also writteninotropics, inotrope, inotropes

Related terms

digoxin

A drug that makes the heart beat more strongly and more slowly.

heart failure

A long-term condition in which the heart cannot pump enough blood to meet the body's needs.

cardiac output

The amount of blood the heart pumps out in one minute.

dobutamine

An IV drug that makes the heart muscle squeeze harder, used for short-term support of a weak heart.

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