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international normalized ratio

A blood test result that shows how long blood takes to clot, reported in a standard way so labs everywhere can compare it.

in-ter-NASH-uh-nul NOR-muh-lyzd RAY-shee-oh noun

What it means

The INR comes from the prothrombin time (PT). Because each lab's PT test differs a little, the result is converted to the INR so that the number means the same thing everywhere. A higher INR means the blood takes longer to clot. It is used mainly to adjust the dose of warfarin, and also to check liver function, since the liver makes clotting factors.

For the nurse

Check the INR before giving warfarin and report a value above the target. Watch for bleeding: gums, nosebleeds, bruising, blood in urine or stool. phytonadionefy-toh-nuh-DY-ohnVitamin K1 given as a drug, by mouth or injection, to help the blood clot.Full entry reverses warfarin.

At a glance

Normal rangeAbout 0.8–1.1 for a person not taking an anticoagulant (it has no units). The usual target on warfarin is 2.0–3.0; some conditions, such as mechanical heart valves, use a higher target.
AbbreviationsINR; PT (prothrombin time)
Also writtenINR, PT/INR

Related terms

anticoagulant

A drug that slows the blood's ability to form clots.

hepatic

Relating to the liver.

clotting

The process by which blood thickens into a gel to plug a damaged vessel and stop bleeding; also called coagulation.

phytonadione

Vitamin K1 given as a drug, by mouth or injection, to help the blood clot.

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