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Dictionary · Drug

isoniazid

An antibiotic used to treat tuberculosis and to keep latent tuberculosis from becoming active.

eye-soh-NY-uh-zid nounBoxed warning

What it means

A core tuberculosistoo-ber-kyoo-LOH-sisAn infection caused by the bacterium Mycobacterium tuberculosis, which most often attacks the lungs.tubercul/o small swelling-osis abnormal conditionFull entry drug, often called INH. Active TB is treated with isoniazid plus other drugs such as rifampinrif-AM-pinAn antibiotic used mainly with other drugs to treat tuberculosis.Full entry ; latent TB may be treated with isoniazid for several months, alone or with another drug. Its boxed warning is for liver damage, which is more likely with age and daily alcohol use. It can also cause nerve damage in the hands and feet, which pyridoxinepeer-ih-DOK-seenVitamin B6, given as a supplement or drug.Full entry (vitamin B6) helps prevent.

For the nurse

Teach the client to take it on an empty stomach every day for the whole course, to avoid alcohol, and to report loss of appetite, nausea, dark urine, yellow skin or numbness and tingling. Liver tests are checked as ordered.

At a glance

Drug classantitubercular
Spanishisoniazida
Also writtenINH

Related terms

tuberculosis

An infection caused by the bacterium Mycobacterium tuberculosis, which most often attacks the lungs.

peripheral neuropathy

Damage to the nerves outside the brain and spinal cord, most often in the feet and hands.

rifampin

An antibiotic used mainly with other drugs to treat tuberculosis.

pyridoxine

Vitamin B6, given as a supplement or drug.

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