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Dictionary · Drug

lactulose

A man-made sugar syrup that draws water into the bowel and lowers ammonia in the blood.

LAK-tyoo-lose noun

What it means

An osmotic laxativeLAK-suh-tivA drug that loosens stool or helps the bowels move, used to treat or prevent constipation.Full entry that the body cannot digest. Gut bacteria break it down into acids, which pull water into the colon and trap ammonia so it leaves in the stool. It is used for long-term constipation and to treat and prevent hepatic encephalopathy, the confusion that liver disease can cause.

For the nurse

For liver disease the dose is adjusted to 2 to 3 soft stools a day; check mental status and ammonia levels. Watch for diarrhea, low potassium and dehydration. Mixing it with juice helps the very sweet taste.

At a glance

Drug classosmotic laxative; ammonia detoxicant
Brand namesEnulose, Constulose, Generlac
Also writtenEnulose, Constulose, Generlac

Related terms

hypokalemia

A blood potassium level below normal, under 3.5 mEq/L.

constipation

Bowel movements that happen less often than usual, with hard, dry stool that is difficult to pass.

laxative

A drug that loosens stool or helps the bowels move, used to treat or prevent constipation.

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