Skip to main content
CSTSetup
Dictionary · Lab

lecithin/sphingomyelin ratio

A test of amniotic fluid that compares two fats found in lung surfactant, used to judge whether a fetus's lungs are mature.

LES-ih-thin sfing-goe-MY-eh-lin RAY-shee-oh noun

What it means

Lecithin and sphingomyelin are parts of surfactant, the substance that keeps the tiny air sacs of the lungs open. Late in pregnancy the lungs make much more lecithin, so the ratio rises. A ratio of 2:1 or more in fluid taken by amniocentesisam-nee-oh-sen-TEE-sisA test in which a needle is put through the belly into the uterus to take a sample of amniotic fluid.amni/o amnion (the sac around the fetus)-centesis puncture to remove fluidFull entry suggests the lungs are mature and the baby is less likely to have breathing trouble after birth. Babies of parents with diabetes may need a higher ratio.

At a glance

Normal range2:1 or higher indicates lung maturity
Also writtenL/S ratio, lecithin-sphingomyelin ratio

Related terms

alveolus

One of the tiny air sacs at the ends of the smallest airways in the lungs.

amniocentesis

A test in which a needle is put through the belly into the uterus to take a sample of amniotic fluid.

Filed under

Look up another word