Nikolsky sign

A finding in blistering skin diseases in which the layers of skin do not hold together, so light pressure makes the outer layer shear away or a blister spread. It is seen in pemphigus vulgaris, toxic epidermal necrolysis and Stevens-Johnson syndrome, and staphylococcal scalded skin syndrome. It is named after Pyotr Nikolsky, a Russian dermatologist.

Handle the skin as little as possible: lift with a sheet rather than sliding, avoid tape on the skin, and use nonstick dressings. Watch fluid balance and signs of infection, since the skin barrier is broken.