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Dictionary · Drug

nonsteroidal anti-inflammatory drug

A drug that relieves pain, fever and inflammation and is not a steroid, such as ibuprofen or naproxen.

non-STAIR-oy-dul an-tee-in-FLAM-uh-tor-ee DRUG nounBoxed warningBeers Criteria

Word parts

non- notanti- againstinflamm/o inflammation

What it means

A group of drugs that block the COX enzymes the body uses to make prostaglandins, the chemicals behind pain, fever and swelling. Members include ibuprofeneye-byoo-PROH-fenA drug that eases pain, fever and inflammation; a nonsteroidal anti-inflammatory drug.Full entry , naproxen, ketorolac, celecoxib and aspirinAS-prinA drug that eases pain, fever and inflammation and makes platelets less sticky so blood clots less easily.Full entry . Main risks are stomach ulcers and bleeding, kidney injury, and (for all but aspirin) a higher risk of heart attack and stroke.

For the nurse

Give with food or milk. Teach the client to report black stools, stomach pain or vomiting blood, and not to take two NSAIDs at once, since many cold remedies contain one. Prescription NSAIDs carry boxed warnings for heart attack, stroke and stomach bleeding, and the Beers Criteria advise against long-term use in older adults.

At a glance

AbbreviationsNSAID
Spanishantiinflamatorio no esteroideo (AINE)
Also writtennonsteroidal anti-inflammatory drugs, NSAID, NSAIDs, non-steroidal anti-inflammatory drug

Related terms

analgesic

A drug that relieves pain.

inflammation

The body's protective response to injury or infection, with redness, heat, swelling, pain and sometimes loss of function.

aspirin

A drug that eases pain, fever and inflammation and makes platelets less sticky so blood clots less easily.

ibuprofen

A drug that eases pain, fever and inflammation; a nonsteroidal anti-inflammatory drug.

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