What it means
N-terminal pro-B-type natriuretic peptide is released along with BNP when the heart's lower chambers are under strain from too much pressure or volume. Higher levels go with more severe heart failurehart FAYL-yerA long-term condition in which the heart cannot pump enough blood to meet the body's needs.Full entry , and falling levels show response to treatment. Age and kidney disease raise it, and obesity lowers it. Unlike BNP, it is not affected by the heart failure drug sacubitril/valsartan.
At a glance
| Normal range | Below 125 pg/mL under age 75; below 450 pg/mL at 75 and older [same values in ng/L]. Ranges vary by lab. |
|---|---|
| Also written | N-terminal pro-BNP |
Related terms
heart failure
A long-term condition in which the heart cannot pump enough blood to meet the body's needs.
pulmonary edema
A buildup of fluid in the air sacs and tissues of the lungs.