Skip to main content
CSTSetup
Dictionary · Drug

paliperidone

A second-generation antipsychotic drug, taken as a daily tablet or given as a long-acting injection.

pal-ee-PAIR-ih-done nounBoxed warningBeers Criteria

What it means

An atypical antipsychotic for schizophrenia and schizoaffective disorder. Long-acting injections, given monthly to every 6 months depending on the product, help people who find daily pills hard to keep up with. Side effects include restlessness, movement problems, raised prolactin, weight gain and higher blood glucose and lipids. It raises the risk of death in older adults with dementia-related psychosis.

For the nurse

The tablets are swallowed whole, never crushed. Give long-acting injections IM at the site and interval ordered, and keep track of the due date. Check weight, glucose and lipids, and watch for stiffness or restlessness.

At a glance

Drug classantipsychotic (second generation, atypical)
Brand namesInvega (extended-release tablet); Invega Sustenna, Invega Trinza, Invega Hafyera, Erzofri (long-acting injections)
Also writtenInvega, Invega Sustenna, Invega Hafyera

Related terms

hallucination

Hearing, seeing, feeling, smelling or tasting something that is not really there.

lurasidone

A second-generation antipsychotic drug taken by mouth for schizophrenia and bipolar depression.

Filed under

Look up another word