What it means
A thiazolidinedione (TZD) for type 2 diabetestipe too dy-uh-BEE-teezA form of diabetes in which the body does not respond well to insulin and does not make enough of it to keep blood glucose normal.Full entry . It lowers insulin resistance in muscle, fat and liver. It works slowly, taking weeks to show its full effect. It causes the body to hold fluid, which can cause weight gain and swelling or worsen heart failurehart FAYL-yerA long-term condition in which the heart cannot pump enough blood to meet the body's needs.Full entry , and it is linked with bone fractures and possibly bladder cancer.
For the nurse
Weigh the client and check for swelling and shortness of breath; report rapid weight gain. Liver tests are checked. Teach the client to report blood in the urine or pain on urination.
At a glance
| Drug class | thiazolidinedione (TZD) |
|---|---|
| Brand names | Actos |
| Also written | Actos |
Related terms
edema
Swelling caused by extra fluid trapped in the body's tissues.
insulin
A hormone made by the pancreas that lets the body's cells take in glucose, also made as a medicine.
heart failure
A long-term condition in which the heart cannot pump enough blood to meet the body's needs.
type 2 diabetes
A form of diabetes in which the body does not respond well to insulin and does not make enough of it to keep blood glucose normal.