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Dictionary · Drug

pravastatin

A statin drug taken by mouth to lower LDL cholesterol and the risk of heart attack and stroke.

PRAV-uh-stat-in noun

What it means

An HMG-CoA reductase inhibitor (statin): it slows the liver's production of cholesterol, lowering LDL ("bad") cholesterol and triglycerides. It is used with diet and exercise to prevent heart attack and stroke. It has fewer drug interactions than some other statins. Side effects include muscle aches and, rarely, liver injury or serious muscle breakdown.

For the nurse

Teach the client to report unexplained muscle pain, tenderness or weakness, especially with fever or dark urine, and yellow skin or eyes. Expect liver tests and a lipid panel. Statins are not taken in pregnancy.

At a glance

Drug classHMG-CoA reductase inhibitor (statin)
Brand namesPravachol
Spanishpravastatina

Related terms

coronary artery disease

Narrowing of the arteries that supply blood to the heart muscle, most often from fatty plaque buildup.

atherosclerosis

A buildup of fatty deposits (plaque) inside the walls of the arteries.

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