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Dictionary · Drug

probenecid

A drug that helps the kidneys get rid of uric acid, taken to prevent gout attacks.

proh-BEN-uh-sid noun

What it means

A uricosuric drug that lowers uric acid in the blood by blocking its reabsorption in the kidney. It is used for long-term gout, not for an acute attack. It also slows the kidney's removal of penicillin, so it is sometimes given to keep penicillin levels higher.

For the nurse

Teach the client to drink 2 to 3 liters of fluid a day to prevent kidney stones, and to avoid aspirin, which blocks its effect. Gout attacks may increase at first.

At a glance

Drug classuricosuric agent

Related terms

aspirin

A drug that eases pain, fever and inflammation and makes platelets less sticky so blood clots less easily.

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