Skip to main content
CSTSetup
Dictionary · Drug

prochlorperazine

A phenothiazine drug used mainly to treat severe nausea and vomiting.

proh-klor-PAIR-uh-zeen nounBoxed warning

What it means

A dopamine blocker related to the older antipsychotic drugs. It is given by mouth, rectal suppository, IM or IV for severe nausea and vomiting and sometimes for migraine, and at higher doses for psychosis. Side effects include drowsiness, low blood pressure on standing and movement problems such as restlessness and muscle spasms.

For the nurse

Watch for sudden muscle spasms of the face, neck or eyes and report them; benztropineBENZ-troh-peenAn anticholinergic drug used to treat movement side effects of antipsychotic drugs and symptoms of Parkinson disease.Full entry or diphenhydramine may be ordered. Have the client rise slowly. Older adults with dementia-related psychosis have a higher risk of death on this class of drug.

At a glance

Drug classantiemetic (phenothiazine)
Brand namesCompazine, Compro (suppository)
Also writtenCompazine, Compro

Related terms

nausea

An uneasy feeling in the stomach with the urge to vomit.

metoclopramide

A drug that speeds emptying of the stomach and lessens nausea by blocking dopamine.

benztropine

An anticholinergic drug used to treat movement side effects of antipsychotic drugs and symptoms of Parkinson disease.

Filed under

Look up another word