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Dictionary · Drug

propranolol

A beta blocker that slows the heart and lowers blood pressure by blocking adrenaline's effects on the heart and lungs.

proh-PRAN-oh-lol nounHigh-alert drugBoxed warning

What it means

A nonselective beta blockerBAY-tuh BLOK-erA drug that blocks the effects of adrenaline on beta receptors, slowing the heart rate and lowering blood pressure.Full entry : it blocks both beta-1 receptors in the heart and beta-2 receptors in the lungs and blood vessels. It is used for high blood pressure, angina, fast heart rhythms, to prevent migraines, for tremor, for the symptoms of an overactive thyroid, and as Hemangeol for a type of birthmark in infants. Because it also acts on the lungs, it can tighten the airways in people with asthma. IV propranolol is on ISMP's high-alert list (IV adrenergic antagonists); the tablets and capsules are not.

For the nurse

Check the apical pulse and blood pressure before each dose and hold it as ordered if they are low. It can hide the fast heartbeat and shakiness of low blood glucose, so teach clients with diabetes to check their glucose. Teach not to stop it suddenly, which can bring on chest pain or a heart attack.

At a glance

Drug classbeta-adrenergic blocker (nonselective)
Brand namesInderal LA, InnoPran XL, Hemangeol
Spanishpropranolol
Also writtenInderal, Inderal LA, Hemangeol

Related terms

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

beta blocker

A drug that blocks the effects of adrenaline on beta receptors, slowing the heart rate and lowering blood pressure.

carvedilol

A beta blocker that also widens blood vessels, taken by mouth for heart failure and high blood pressure.

atenolol

A beta blocker taken by mouth that slows the heart and lowers blood pressure, acting mainly on the heart.

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