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Dictionary · Drug

pyrazinamide

An oral antitubercular drug used for the first 2 months of treatment for active tuberculosis.

peer-uh-ZIN-uh-mide noun

What it means

One of the four first-line drugs for active tuberculosistoo-ber-kyoo-LOH-sisAn infection caused by the bacterium Mycobacterium tuberculosis, which most often attacks the lungs.tubercul/o small swelling-osis abnormal conditionFull entry , given with isoniazid, rifampin and ethambutoleh-THAM-byoo-tolAn oral antitubercular drug used with other drugs to treat tuberculosis.Full entry in the first phase of treatment. It can damage the liver and raises uric acid, which can bring on gout and joint pain.

For the nurse

Liver tests and uric acid are checked. Teach the client to avoid alcohol, to drink plenty of fluids, and to report yellow skin or eyes, dark urine, loss of appetite or painful joints.

At a glance

Drug classantitubercular agent
Also writtenPZA

Related terms

pulmonary tuberculosis

Tuberculosis of the lungs, caused by the bacterium Mycobacterium tuberculosis.

streptomycin

An aminoglycoside antibiotic given by injection, used mainly for tuberculosis and a few rare infections.

ethambutol

An oral antitubercular drug used with other drugs to treat tuberculosis.

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