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Dictionary · Eponym

Reye syndrome

A rare illness that causes swelling of the brain and liver damage, mostly in children and teenagers.

RYE SIN-drohm noun

What it means

Named after Douglas Reye, the Australian doctor who described it in 1963. It usually begins as a child is getting over a viral illness such as the flu or chickenpox, and it has been strongly linked to taking aspirin during that illness. Vomiting, confusion, lethargy and changes in behavior can progress to seizures and coma.

For the nurse

Teach families not to give aspirin or other salicylates (including bismuth subsalicylate, such as Pepto-Bismol) to children and teenagers unless a provider orders it, and to check the labels of cold medicines.

At a glance

Spanishsíndrome de Reye
Also writtenReye's syndrome, Reye’s syndrome

Related terms

aspirin

A drug that eases pain, fever and inflammation and makes platelets less sticky so blood clots less easily.

influenza

An infection of the nose, throat and lungs caused by influenza viruses; the flu.

varicella-zoster virus

The virus that causes chickenpox and, years later, can wake up again to cause shingles.

encephalopathy

A general term for any disease or damage that changes how the brain works.

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