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Dictionary · Drug

risperidone

A second-generation antipsychotic used for schizophrenia, bipolar mania and irritability in autism.

ris-PAIR-ih-dohn nounBoxed warningBeers Criteria

What it means

An atypical antipsychotican-tee-sy-KOT-ikA drug used to treat psychosis, such as hallucinations and delusions, in conditions like schizophrenia and bipolar disorder.Full entry that blocks dopamine and serotonin receptors. It comes as tablets, tablets that melt on the tongue, a liquid and long-acting injections. Side effects include weight gain, higher blood sugar and cholesterol, high prolactin (breast swelling, milk discharge, missed periods), dizziness on standing and, at higher doses, movement problems. It carries the antipsychotic boxed warning for a higher death rate in older adults with dementia-related psychosis. Its name can be confused with ropiniroleroh-PIN-ih-rohlA drug that acts like dopamine in the brain, used for Parkinson disease and for restless legs syndrome.Full entry .

For the nurse

Check weight, blood glucose, cholesterol and blood pressure at the start and during treatment. Watch for stiffness, restlessness and unusual movements, and report a high fever with rigid muscles at once. Teach the client to rise slowly.

At a glance

Drug classsecond-generation (atypical) antipsychotic
Brand namesRisperdal, Risperdal Consta
Spanishrisperidona
Also writtenRisperdal, Risperdal Consta

Easy to confuse with

ropinirole

A drug that acts like dopamine in the brain, used for Parkinson disease and for restless legs syndrome.

Related terms

bipolar disorder

A mental health condition with periods of very high mood and energy (mania) and, often, periods of depression.

schizophrenia

A long-term mental illness that changes a person's thinking, feelings and behavior, often with a loss of contact with reality.

antipsychotic

A drug used to treat psychosis, such as hallucinations and delusions, in conditions like schizophrenia and bipolar disorder.

tardive dyskinesia

A movement disorder with repeated movements a person cannot control, most often of the face, lips and tongue.

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