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sepsis

A severe whole-body response to an infection that damages the body's own organs.

SEP-sis noun

What it means

An infection sets off a reaction in the whole body that harms organs such as the kidneys, lungs and brain. Signs include fever or a low temperature, a fast heart and breathing rate, low blood pressure, confusion and low urine output. When blood pressure stays low despite fluids, it is septic shock. A high blood lactate level is one of the lab signs.

For the nurse

Sepsis care is time-critical: the first-hour bundle includes a lactate level, blood cultures before antibiotics, broad-spectrum antibiotics and IV fluids. Report early warning signs, such as new confusion, a rising breathing rate or falling blood pressure, at once.

In a chart

"Temp 39.1 °C, HR 122, BP 86/50, new confusion; sepsis bundle started."

At a glance

Spanishsepsis
Also writtenseptic, septicemia

Related terms

hypotension

Blood pressure lower than normal, generally below 90/60 mm Hg in an adult.

bacterium

A tiny one-celled living thing, seen only under a microscope, of which some kinds cause disease; the plural is bacteria.

infectious disease

An illness caused by a germ such as a bacterium, virus, fungus or parasite.

pathogen

A germ, such as a bacterium, virus, fungus or parasite, that can cause disease.

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