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Dictionary · Drug

succinylcholine

A fast, short-acting drug that relaxes and paralyzes the muscles, used to place a breathing tube.

suk-sih-nil-KOH-leen nounHigh-alert drugBoxed warning

What it means

A depolarizing neuromuscular blocker. It works within about a minute and wears off in several minutes, so it is used for rapid-sequence intubation and short procedures. Muscles twitch briefly (fasciculations) before they go limp. It does not cause sleep or relieve pain. It can raise the blood potassium and can trigger malignant hyperthermiamuh-LIG-nunt hy-per-THER-mee-uhA rare inherited reaction to certain general anesthesia drugs in which the muscles' metabolism speeds up out of control.mal- badhyper- above normaltherm heat-ia conditionFull entry in people at risk.

For the nurse

It is given only where breathing can be fully supported, and always with a sedative, since the client cannot move or breathe but may be aware. Store and label it carefully as a paralyzing agent. Watch for high potassium in clients with burns, crush injuries or nerve damage.

At a glance

Drug classneuromuscular blocking agent (depolarizing)
Brand namesAnectine, Quelicin
Spanishsuccinilcolina
Also writtenAnectine, Quelicin

Related terms

hyperkalemia

A blood potassium level above normal, over 5.0 mEq/L.

anesthesia

Loss of feeling or sensation, often brought on by drugs so that surgery or a procedure can be done without pain.

malignant hyperthermia

A rare inherited reaction to certain general anesthesia drugs in which the muscles' metabolism speeds up out of control.

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