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Dictionary · Drug

tadalafil

A PDE5 inhibitor: a drug that relaxes smooth muscle in blood vessels, used for erectile dysfunction, enlarged prostate and pulmonary hypertension.

tuh-DAL-uh-fil noun

What it means

A drug that increases blood flow by blocking the enzyme phosphodiesterase-5. It treats erectile dysfunction, the urinary symptoms of benign prostatic hyperplasiabee-NINE proh-STAT-ik hy-per-PLAY-zhuhA prostate gland that has grown larger than normal, from growth that is not cancer.hyper- more than normalplas growth or formation-ia conditionFull entry , and pulmonary arterial hypertension (as Adcirca or Alyq). It lasts up to 36 hours. Headache, flushing, back pain and stuffy nose are common.

For the nurse

Ask about nitrate use: taking it with nitrates such as nitroglycerin or isosorbide dinitrateeye-soh-SOR-bide dy-NY-trateA long-acting nitrate drug, taken by mouth, that widens blood vessels to prevent chest pain from angina.Full entry can cause a dangerous drop in blood pressure. Teach the client to get emergency help for an erection lasting over 4 hours or sudden vision or hearing loss.

At a glance

Drug classphosphodiesterase-5 (PDE5) inhibitor
Brand namesCialis, Adcirca, Alyq
Also writtenCialis, Adcirca, Alyq

Related terms

hypotension

Blood pressure lower than normal, generally below 90/60 mm Hg in an adult.

benign prostatic hyperplasia

A prostate gland that has grown larger than normal, from growth that is not cancer.

isosorbide dinitrate

A long-acting nitrate drug, taken by mouth, that widens blood vessels to prevent chest pain from angina.

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