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titrate

To adjust the dose or rate of a drug step by step until the wanted effect is reached.

TY-trayt verb

What it means

To raise or lower a dose in small amounts while watching the client's response. IV drips are often titrated to a target, such as a blood pressure, heart rate or oxygen saturation. Oxygen can be titrated to a saturation goal. Some oral drugs are titrated up slowly over weeks to limit side effects.

For the nurse

Follow the order or protocol for the starting dose, how much to change it, how often and the target. Check the client's response (such as blood pressure) at each step and document each change.

In a chart

"Norepinephrine titrated per protocol to maintain MAP above 65 mm Hg."

At a glance

Spanishtitular, ajustar la dosis
Also writtentitrated, titrating, titration, titrations

Related terms

oxygen

A gas in the air that every cell needs, also given as a medicine at higher amounts than room air.

monitor

To watch, check or measure something again and again over a period of time.

infusion

The slow delivery of a fluid or drug into the body, usually into a vein, over a period of time.

bolus

A single amount of a drug or fluid given all at once or over a short time.

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