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total protein

A blood test that measures all the protein in the serum, mainly albumin and globulins.

TOH-tul PROH-teen noun

What it means

The two main groups of blood proteins are albumin, which holds fluid inside the blood vessels, and globulins, which include the antibodies. The total protein test adds them up. It is often part of a liver or comprehensive metabolic panel. It can be low with poor nutrition, liver disease, kidney disease that leaks protein, or severe burns, and high with dehydration or some long-term infections and blood cancers.

For the nurse

Look at it with the albumin level, weight and diet history when assessing nutrition. A low protein level can lead to swelling and slow wound healing.

At a glance

Normal rangeAbout 6.0–8.3 g/dL [60–83 g/L]; each lab sets its own range.
Also writtenserum protein, serum proteins

Related terms

amino acid

One of the small building blocks that join together in chains to make proteins.

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