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Dictionary · Drug

trazodone

An antidepressant drug, often given in low doses at bedtime to help with sleep.

TRAZ-uh-dohn nounBoxed warning

What it means

A serotonin-modulating antidepressant approved for depression and widely used at lower doses for insomnia. Side effects include drowsiness, dizziness, dry mouth and low blood pressure on standing. A rare but urgent side effect is priapism, a painful erection that lasts for hours.

For the nurse

Give at bedtime and teach the client to get up slowly; watch older adults for falls. Like all antidepressants, it carries a boxed warning about suicidal thoughts in young people. Teach male clients to seek emergency care for an erection lasting more than 4 hours.

At a glance

Drug classantidepressant (serotonin modulator)
Brand namesDesyrel
Spanishtrazodona
Also writtenDesyrel

Easy to confuse with

tramadol

An opioid pain drug, taken by mouth, for moderate to severe pain.

quetiapine

A second-generation antipsychotic drug used for schizophrenia, bipolar disorder and, with other drugs, depression.

Related terms

antidepressant

A drug used to treat depression and often anxiety, which works by changing the levels of brain chemicals such as serotonin.

sedation

A calm, relaxed or sleepy state brought on by drugs, or the use of drugs to cause it.

sertraline

An SSRI antidepressant used for depression, anxiety disorders, OCD and PTSD.

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