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Dictionary · Drug

zafirlukast

A tablet that blocks leukotrienes, chemicals that narrow and inflame the airways, used to prevent asthma attacks.

zuh-FEER-loo-kast noun

What it means

A leukotriene receptor antagonist taken twice a day for long-term asthma control. It prevents symptoms but does not stop an attack that has started. It can rarely injure the liver and can raise the effect of warfarin.

For the nurse

Give it at least 1 hour before a meal or 2 hours after one, since food lowers how much is absorbed. Teach the client to keep a rescue inhaler and to report upper right belly pain, dark urine or yellow skin.

At a glance

Drug classleukotriene receptor antagonist
Brand namesAccolate
Also writtenAccolate

Related terms

wheezing

A high-pitched, whistling sound made as air moves through narrowed airways.

inhalation

Breathing in; also, a way of giving a drug as a mist or powder that is breathed into the lungs.

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