What it means
A tricyclic antidepressanttry-SY-klik an-tee-dih-PRES-entAn older type of antidepressant, named for its three-ring chemical structure, also used for nerve pain.Full entry that raises serotonin and norepinephrine in the brain. It has strong anticholinergic effects (dry mouth, constipation, trouble passing urine, blurred vision), causes sleepiness and dizziness on standing, and can cause weight gain. An overdose can cause dangerous heart rhythms and seizures. Like other antidepressants, it carries a boxed warning about suicidal thinking in young people.
For the nurse
Give it at bedtime if it causes sleepiness. Teach the client to stand up slowly, drink fluids and eat fiber, and not to stop it suddenly. For a client at risk of suicide, the supply may be limited because of its danger in overdose.
At a glance
| Drug class | tricyclic antidepressant |
|---|---|
| Brand names | Elavil (former US brand) |
| Spanish | amitriptilina |
| Also written | Elavil |
Related terms
antidepressant
A drug used to treat depression and often anxiety, which works by changing the levels of brain chemicals such as serotonin.
depression
A mood disorder of lasting sadness or loss of interest that affects thinking, sleep, appetite and daily life.
tricyclic antidepressant
An older type of antidepressant, named for its three-ring chemical structure, also used for nerve pain.