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Dictionary · Drug

colchicine

A drug that treats and prevents gout attacks by calming inflammation in the joints.

KOL-chih-seen noun

What it means

It stops white blood cells from rushing into a joint where uric acid crystals have formed. It works best when started within the first day or so of a goutgowtA form of arthritis in which crystals of uric acid collect in and around a joint.Full entry flare, and in lower daily doses it prevents flares. It is also used for some other inflammatory conditions, such as pericarditis. The gap between a helpful and a toxic dose is small: diarrhea, nausea and vomiting are common and can be early signs of toxicity. Many drugs, and grapefruit, raise its level.

For the nurse

Teach the client to take only the dose prescribed, to stop and call the provider for severe diarrhea or vomiting, muscle weakness or unusual bleeding, and to check with a pharmacist before starting other medicines.

At a glance

Drug classantigout agent (anti-inflammatory)
Brand namesColcrys, Mitigare, Gloperba, Lodoco
Spanishcolchicina
Also writtenColcrys, Mitigare, Gloperba, Lodoco

Related terms

gout

A form of arthritis in which crystals of uric acid collect in and around a joint.

uric acid

A waste product made when the body breaks down purines, measured with a blood test.

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