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diabetic ketoacidosis

A state of high blood glucose, ketones in the blood and acidic blood, caused by a lack of insulin.

dy-uh-BET-ik kee-toh-as-ih-DOH-sis noun

Word parts

What it means

When the body has almost no insulinIN-suh-linA hormone made by the pancreas that lets the body's cells take in glucose, also made as a medicine.Full entry , cells cannot use glucose, so the body burns fat for energy instead. Burning fat makes ketones, which are acids, and the blood becomes too acidic. Typical findings are a blood glucose above 250 mg/dL, a blood pH of 7.3 or lower, and ketones in the blood and urine. It develops quickly, often within a day, and is most common in type 1 diabetes, often set off by infection or missed insulin.

For the nurse

Look for thirst, much urination, nausea and vomiting, belly pain, fruity breath and deep, rapid Kussmaul respirationsKOOS-mowl res-puh-RAY-shunzA breathing pattern of deep, rapid, labored breaths at an even pace.Full entry . Treatment is IV fluids, IV regular insulin and potassiumpuh-TAS-ee-umA mineral in the blood that nerves and muscles, including the heart, need in order to work.Full entry replacement, so check glucose hourly and potassium often: insulin moves potassium into the cells and the level can drop fast.

In a chart

"Glucose 486 mg/dL, pH 7.18, urine ketones large; insulin infusion started per DKA protocol."

At a glance

AbbreviationsDKA
Spanishcetoacidosis diabética
Also writtenDKA, diabetic ketoacidoses

Easy to confuse with

HHS

Hyperosmolar hyperglycemic state: very high blood glucose with severe dehydration and little or no ketone buildup.

Related terms

Kussmaul respirations

A breathing pattern of deep, rapid, labored breaths at an even pace.

insulin

A hormone made by the pancreas that lets the body's cells take in glucose, also made as a medicine.

-osis

A word ending that means an abnormal condition or process, or an increase.

hyperglycemia

A blood glucose level above normal, over 100 mg/dL when fasting.

type 1 diabetes

A form of diabetes in which the pancreas makes little or no insulin because the immune system has destroyed the cells that make it.

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